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Karami S, Lashtoo Aghaee B, Ghobadi N, Karami H, Eftekhari K, Lashtoo Aghaee B. Saliva and its role in diagnosis dental caries and periodontitis. Clin Exc 2017; 6 (2) :39-48
URL: http://ce.mazums.ac.ir/article-1-327-en.html

Saliva is a complex fluid consisting of secretions from the major and minor salivary glands. Similarly to blood, saliva, is consist of enzymes, hormones, antibodies, anti-microbial components and growth factors. Saliva, as a diagnostic fluid, has distinctive advantages over serum as whole saliva can be collected noninvasively by individuals with limited training using simple equipment’s. Dental caries and periodontitis are important oral infections that if we can diagnose them as soon as possible, prevention may occur. In this study, we Searched data base such as PubMed, Elsevier, Scopus, and Google scholar to have comprehensive review on diagnostic role of saliva in dental caries and periodontitis. Nowadays, biomarkers in saliva are important clues in diagnosis. They are especially used in oral infections detection and prognosis.  On the other hand, analysis of saliva can offer a cost-effective approach to screen for a larger population. So, improvement of using saliva and detecting biomarkers can be a helpful and useful step in diagnosis dental caries and periodontitis.