Insulin resistance in patients with diabetes mellitus Cause complications such as cardiovascular disease and kidney. The studies have indicated that ginseng is effective in hyperglycemia control and prevention of the complications of diabetes through improving insulin sensitivity and reduce blood pressure, inflammation, oxidative stress, dyslipidemia and obesity. The current study aimed to review the available studies regarding the effect of ginseng on improving glycemic status and other related parameters. This review study was done by searching on PubMed, Scopus, Science Direct and Persian databases as the SID and Magiran by using of key words: Inflammation, Ginseng, Obesity, Type 2 diabetes, Dyslipidemia. In this study, the articles published between the years 1995-2014 were used. The study’s results show that ginseng and ginsenosids (active compunds of ginseng) can reduce hyperglycemia, hypertension, inflammation, oxidative stress, dyslipidemia and obesity in patients with Type 2 diabetes. Although some studies did not support the effects of ginseng. One of the reasons for inconsistent results between studies is different combinations between types of ginseng (Asian, American, ...) So, due to few studies and conflicting results in this regard, more research is suggested.