Volume 7, Issue 1 (7-2017)                   Clin Exc 2017, 7(1): 1-12 | Back to browse issues page

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Mahdavi H, Ahmadi M, Hadad Z. Effective Compounds of prevention and treatment of Prostate disorders. Clin Exc 2017; 7 (1) :1-12
URL: http://ce.mazums.ac.ir/article-1-339-en.html
Research & Development Department, Sinafaravar pharmaceutical Company, Najaf abad, Esfahan, Iran.
Abstract:   (14531 Views)
   Benign prostatic hyperplasia (BPH) is a common disease in elderly men also cancer prostate is the most common malignancy in males of developed countries. Different Natural supplements have been found to effect the growth and proliferation of prostate cancer cells as evident in epidemiological, experimental and clinical studies. There is good evidence of protective effects of Natural supplements against prostate cancer are Explained.
In this paper, using online databases Iranmedex Pubmed, Medline, Google scholar, Scopous, Science direct, SID and Iranmedex on various aspects of medicinal plant stinging nettle was proposed up to 2016, with using keywords Benign prostatic hyperplasia, Urtica dioica, Saw palmetto, Pygeum africanum, Cucubita pepo, VitE and Vit B6 therapeutic effect and medicinal plant were studied.
Urtica dioica can be used as an effective drug for the management of Prostate disorders. Effects of U.dioica on benign induced by testosterone have been exhibited. Studies were conducted to assess the 5α-reductase inhibitory potential of this plant. Saw palmetto is an herbal product used in the treatment of symptoms related to benign Prostate disorders.  Saw palmetto appears to have efficacy similar to that of medications like finasteride, but it is better tolerated and less expensive. Pumpkin seed extracts (Cucurbita pepo) contain oily substance composed of linolic acid sterols, seleneniume, magnesium and carotinoid that they have mechanism of action is thought to be antiandrogenic and antiphlogistic. Furthermore, many vitamins and chemicals, including vitaminE, vitaminB6 and Zinc have shown their anticancer activities as anti-oxidants. The use of medicinal herbs with BPH therapeutic properties can be used as a substitute or complementary of the chemical drugs that are effective in the treatment of prostate disorders.
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Type of Study: Review | Subject: فارماکوگنوزی(تهیه دارو از منابع طبیعی)
Received: 2017/01/12 | Accepted: 2017/07/3 | Published: 2017/07/3

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