<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Clinical Excellence</title>
<title_fa>تعالی بالینی</title_fa>
<short_title>Clin Exc</short_title>
<subject>Medical Sciences</subject>
<web_url>http://ce.mazums.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>2322-391x</journal_id_issn>
<journal_id_issn_online>2322-3928</journal_id_issn_online>
<journal_id_pii>8</journal_id_pii>
<journal_id_doi>7</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid>14</journal_id_sid>
<journal_id_nlai>8888</journal_id_nlai>
<journal_id_science>13</journal_id_science>
<language>fa</language>
<pubdate>
	<type>jalali</type>
	<year>1393</year>
	<month>9</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2014</year>
	<month>12</month>
	<day>1</day>
</pubdate>
<volume>3</volume>
<number>1</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>fa</language>
	<article_id_doi></article_id_doi>
	<title_fa> مروری بر اثرات عصاره زعفران و اجزای آن بر فاکتورهای مرتبط با بیماری‌های سیستم عصبی، قلبی عروقی و گوارشی</title_fa>
	<title>Review on the effects of saffron extract and its constituents on factors related to nervous system, cardiovascular and gastrointestinal diseases</title>
	<subject_fa>شیمی دارویی </subject_fa>
	<subject>شیمی دارویی </subject>
	<content_type_fa>مروری</content_type_fa>
	<content_type>Review</content_type>
	<abstract_fa>&lt;p align=&quot;justify&quot; style=&quot;DIRECTION: rtl&quot;&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;تاکنون اثرات پیشگیرانه و درمانی زیادی از زعفران دیده شده است. امّا مطالعات اندکی این اثرات را به صورت منظم بررسی کرده&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;اند. مطالعه حاضر اثر عصاره زعفران و اجزای آن را بر فاکتورهای مرتبط با بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های سیستم عصبی، قلبی عروقی و گوارشی مرور کرده است. جستجوی مقالات انگلیسی از پایگاه&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های &lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 10pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;Pub Med&lt;/span&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt; و &lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 10pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;Science Direct&lt;/span&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 10pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt; &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;با کمک &lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 10pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;Mesh&lt;/span&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt; و مقالات فارسی از پایگاه &lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 10pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;SID&lt;/span&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 10pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;&lt;span dir=&quot;rtl&quot;&gt;&lt;/span&gt; &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;صورت گرفت.&lt;/span&gt;&lt;span dir=&quot;ltr&quot;&gt;&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;&lt;span dir=&quot;ltr&quot;&gt;&lt;/span&gt; &lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;نتایج نشان می&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;دهد زعفران و اجزای آن می&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;توانند در پیشگیری و درمان بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های مربوط به حافظه و بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های چشمی اثرات مفیدی داشته باشند. هرچند در مورد اثرات ضد&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;درد، ضد&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;التهاب و ضد&lt;/span&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;تشنج زعفران مطالعات محدودی صورت گرفته، امّا نتایج آنها امیدبخش بوده است. اثر زعفران و اجزای آن بر اضطراب و بی&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;خوابی تنها در مطالعات حیوانی بررسی شده و نتایج مفیدی دیده شده است. اثرات ضد&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: AR-SA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;افسردگی آنها نیز در مطالعات بسیار مشهود است. از سوی دیگر اثرات زعفران و اجزای فعال آن در پیشگیری و درمان بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های قلبی عروقی در مطالعات دیده شده است. در مورد اثرات زعفران بر بیماری های گوارشی مطالعاتی محدود و تنها حیوانی صورت گرفته و فواید بالقوه&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;ای در پیشگیری و درمان دیده شده است. زعفران همچنین در مقادیر مصرف روزانه غیرسمی است. در مجموع به نظر می&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;رسد زعفران و اجزای فعال آن در بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های مرتبط با سیستم عصبی، بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های قلبی عروقی و بیماری&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;های گوارشی نقش پیشگیرانه و درمانی داشته باشند. این عملکردها را به خواص آنتی&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;اکسیدانی، ضد&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;التهابی و ضد&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;آپوپتوزی آنها نسبت می&lt;/span&gt;&lt;sub&gt;&lt;span style=&quot;FONT-FAMILY: &quot;Times New Roman&quot;,&quot;serif&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-bidi-font-family: 'B Zar' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot;&gt;­&lt;/span&gt;&lt;/sub&gt;&lt;span lang=&quot;FA&quot; style=&quot;FONT-FAMILY: &quot;B Zar&quot; LETTER-SPACING: -0.2pt FONT-SIZE: 12pt mso-fareast-font-family: 'Times New Roman' mso-ascii-font-family: 'Times New Roman' mso-hansi-font-family: 'Times New Roman' mso-ansi-language: EN-US mso-fareast-language: EN-US mso-bidi-language: FA&quot; dir=&quot;rtl&quot;&gt;دهند.&lt;/span&gt;&lt;/p&gt;</abstract_fa>
	<abstract>&lt;p&gt;  Previous studies have detected preventive and therapeutic effects of saffron. However, no systematic reviews were written on these effects. This study reviews the impact of saffron extract and its' constituents on the factors associated with the nervous system, cardiovascular, and gastrointestinal tract diseases. Articles in English have searched at Pub Med and Science direct databases using Mesh words and Persian articles have searched in SID database. Results indicated that saffron and its' constituents have beneficial effects on preventing and treating of memory-associated diseases and eye disorders. Although, limited investigations were performed on analgesic, anti-inflammatory and anti-seizure effects of saffron, their results were promising. &lt;/p&gt;&lt;p&gt;  The effects of saffron and its’ constituents on anxiety and insomnia were only studied in animal models and the results were promising. Their antidepressant effects became evident in the studies. Moreover, effects of saffron and its active constituents on prevention and treatment of cardiovascular disease have been observed in previous studies. However, few studies were performed on the effects of saffron on gastrointestinal diseases which are limited to animal studies, some potential benefits of saffron in the prevention and treatment of gastrointestinal diseases have been found. Saffron is also non-toxic in doses of daily intake. Collectively, it seems that saffron and its active constituents play preventive and therapeutic roles in the nervous system, cardiovascular and gastrointestinal diseases. These functions emerge from antioxidant, anti-inflammatory and anti-apoptotic properties of saffron. &lt;/p&gt;&lt;p&gt;  &lt;/p&gt;</abstract>
	<keyword_fa>بیماری قلبی عروقی, بیماری‌های سیستم عصبی, بیماری‌های گوارشی, زعفران</keyword_fa>
	<keyword>Cardiovascular Disease, Gastrointestinal Diseases, Nervous System Diseases, Saffron.</keyword>
	<start_page>108</start_page>
	<end_page>127</end_page>
	<web_url>http://ce.mazums.ac.ir/browse.php?a_code=A-10-26-26&amp;slc_lang=fa&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Alireza </first_name>
	<middle_name></middle_name>
	<last_name>Milajerdi</last_name>
	<suffix></suffix>
	<first_name_fa>علیرضا</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>میلاجردی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code>1003194753284600650</code>
	<orcid>1003194753284600650</orcid>
	<coreauthor>No</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Maryam</first_name>
	<middle_name></middle_name>
	<last_name>Mahmoudi</last_name>
	<suffix></suffix>
	<first_name_fa>مریم</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>محمودی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>Mahmoodi_Maryam@yahoo.com</email>
	<code>1003194753284600651</code>
	<orcid>1003194753284600651</orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation></affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
