Personalized medicine is a new insight of health care in which interventions is informed by each patient's characteristics including in genotype and phenotype. Nowadays, rapid advances in genomics, proteomics, and lipomics, which identified individuals differences may lead to produce new drug and diagnostic and screening biomarkers. These allow physicians to determine the type and dosage of drugs based on genetic and genomic characteristics of each patient. Genetic variants that identified by using molecular analysis can be used to screen at risk people on the particular disease, design and administer appropriate medications that are fit to the genetic background , and select the best treatment protocol. Actually, personalized medicine will be the bridge between current medicine and future medicine.

  In addition to a brief review of history of personalized medicine, this review focused on its required technologies, the role of personalized medicine in pharmacogenetics, prognostic, diagnostic, and target therapy of cancer, neurodegenerative, cardiovascular, allergic and infectious diseases