Seizure is one of the most common neurological disorders, and its correct diagnosis and differentiation from other similar disorders is crucial for the proper management of patients. Given the high prevalence of drug-resistant epilepsy and the current possibility of epileptogenic focus surgery, paraclinical methods, such as video-electroencephalography monitoring, are now available to accurately localize the epileptogenic zone. One of the most important components influencing preoperative decision-making in these patients is the knowledge related to seizure semiology, which is necessary for the localization and lateralization of the seizure-onset zone. Therefore, adequate knowledge of the ictal signs and symptoms is considered a fundamental necessity in the diagnosis and treatment of patients with epilepsy. This review article was conducted through searches in the PubMed and Scopus databases within the timeframe of 2004 to 2024. After reviewing the abstracts and full texts of the articles, 68 publications were selected. The results showed that the characteristics of seizure, including precipitating factors, initial symptoms, ictal semiology, and postictal findings, were helpful in distinguishing it from imitators, such as syncope and psychogenic non-epileptic seizures. The details of the seizure semiology and their usefulness in localizing the seizure-onset zone were discussed, and relevant signs and their interpretation were summarized. Based on the findings, it can be concluded that an accurate knowledge of the clinical manifestations and signs of seizures is beneficial for both the correct diagnosis and localization. Thus, a thorough history and, if necessary, the observation of seizures by video-electroencephalography monitoring may be helpful in the diagnosis of patients.
Type of Study:
Review |
Subject:
بيماريهاي مغز و اعصاب (نورولوژی) Received: 2024/05/4 | Accepted: 2024/09/7 | Published: 2024/09/7