Volume 14, Issue 4 (3-2025)
Clin Exc 2025, 14(4): 64-77 |
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Alizadeh-Navaei R, Shekarriz R, Hedayatizadeh-omran A, Ehsani Z. Chemotherapy-Induced Peripheral Neuropathy: A Review of Existing Treatment Approaches with Emphasis on Complementary Medicine. Clin Exc 2025; 14 (4) :64-77
URL: http://ce.mazums.ac.ir/article-1-865-en.html
URL: http://ce.mazums.ac.ir/article-1-865-en.html
Institute of Non-Communicable Diseases, Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Abstract: (12 Views)
Chemotherapy in cancer, while being vital to life-saving, holds severe side effects that can potentially harm patients' quality of life. Among the serious complications that arise after chemotherapy is chemotherapy-induced neuropathy (CIPN), a major problem in the treatment of cancer. This prevalent side effect manifests through a range of sensory, motor, and autonomic symptoms, which can potentially lead to permanent functional impairment, highlighting the need for effective management strategies Moreover, the existing treatment methods largely aim at symptom minimization without fixing the underlying causes. In recent years, there has been growing interest in the potential of natural products as interventions for the CIPN prevention and treatment. Different phytochemicals, dietary supplements, and plant extracts have shown promising outcomes in preclinical and clinical studies due to their anti-inflammatory, antioxidant, and neuroprotective properties. The present review article aimed to provide a comprehensive understanding of the potential benefits, limitations, and future directions for integrating natural products into the management protocols of CIPN.
Type of Study: Review |
Subject:
هماتولوژی و آنکولوژی
Received: 2024/12/3 | Accepted: 2025/04/24 | Published: 2025/04/24
Received: 2024/12/3 | Accepted: 2025/04/24 | Published: 2025/04/24
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