Volume 1, Issue 1 (winter 2013)
Clin Exc 2013, 1(1): 83-102 |
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ghaffari J. Acute chronic urticarial: review of etiology, pathogenesis, manifestation and treatment. Clin Exc 2013; 1 (1) :83-102
URL: http://ce.mazums.ac.ir/article-1-29-en.html
URL: http://ce.mazums.ac.ir/article-1-29-en.html
Abstract: (31037 Views)
Abstract
Urticaria is a common skin disorder the estimate prevalence is 0.3 to 11.3 percent and it
affects up to 20% of the general population during their lifetime. Acute urticaria less than 6
weeks is more common. Chronic urticaria with or without angioedema, which is defined as
wheals with at least 2 times in a week appearance for more than 6 weeks with prevalence of
0.1 perecent The size of lesion is from milimeters to centimeters.
Angioedma is associated in 30 to 50 percent of urticaria. Duration of urticarial is variable
from some weeks to some years. Any age can be involved but it is common in middle middle
aged females. There is not any known etiology in most patients. At present, autoimmune
factors cause 40-50 perecent of it.It does not cause mortality except in anaphylaxis. It is a
benign disease but it causes significant impairment in patients’quality of life (personal
activities, social and spiritual). Exact pathophysiology and etiology in most of chronic
urticarial is not known howevert, different factors such as IgG1 or IgG3 subclasses against
Fc R1 and IgE are involved.
Subject:
اپيدميولوژي
Received: 2013/01/13 | Accepted: 2013/08/27 | Published: 2013/08/27
Received: 2013/01/13 | Accepted: 2013/08/27 | Published: 2013/08/27
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