Renal failure is  a commonly and chronic disease. Dialysis is routine treatment for these patients. Adherence to treatment status is one of the problems of patient on dialysis. The aim at this study is determining of  the most important causes of non-adherence in patients on dialysis, according to previous studies in Iran. At first all of the studies related to our title by using some keywords(dialysis, hemodialysis, adherence, and non-adherence) searched for Iranian databases; iranmedex, magiran, SID, Iran doc, google, google scholar. Inclusion and exclusion criteria were: 1. Publish articles related to adherence or non-adherence in Iran, Articles were Persian (published in Iran),Types of articles were original and All the articles were free full text and downloadable. As a result, related to inclusion and exclusion criteria 13 articles were found and analysises.  The most important reasons for non-adherence to treatment were: psychological reasons (often depression), Lack of awareness and attitude of dialysis patients and lack of social support. Treatment for adherence is so important and can very significant role in health improvement in patients on dialysis.