Volume 10, Issue 1 (4-2020)                   Clin Exc 2020, 10(1): 1-20 | Back to browse issues page

XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Afshar P, Shokrzadeh M, Roozbeh Nasiraie L, Ghorbani-HasanSaraei A, Naghizadeh Raeisi S, Alimi M. Antioxidants protective effects on oxidative stress damage induced by mycotoxins: A Review. Clin Exc 2020; 10 (1) :1-20
URL: http://ce.mazums.ac.ir/article-1-501-en.html
Assistant Professor,Department of Food Science and Technology, Nour Branch, Islamic Azad University, Nour, Iran.
Abstract:   (2705 Views)

Oxidative stress identifies as the imbalance of free radicals (reactive oxygen and nitrogen species) and antioxidants defence. Cellular and tissue damage of oxidative stress causes enhances lipid peroxidation, DNA and protein damage and in finally cell death. Different exo/endogenous factors such as mycotoxins play a role in causing damage mechanism with an increase or decrease the level of the vital molecule such as malondialdehyde (MDA) and glutathione (GSH). Mycotoxins are one of the most common foods and feed contaminants in the world, which considered a serious risk factor for human and animal health. Several enzymatic and/or nonenzymatic natural compounds with antioxidant activity could be inhibiting/reducing oxidative stress damage severity due to the free radical’s imbalance via different mechanisms.

The present study briefly reviews the oxidative stress of major mycotoxins as a potential pathogenic mechanism, and the protective role of some natural plant and microbial compounds with antioxidant capacity (either separately or in combination) in reducing the adverse effects of the above stress. The use of natural and indigenous compounds with antioxidant properties in each region can be considered in the strategies for discovering and producing novel medicines and processed foods that have a protective/therapeutic role as one of the goals of green government establishment in macro-management policies in the country.

Full-Text [PDF 717 kb]   (4592 Downloads)    
Type of Study: case report | Subject: سم شناسی
Received: 2019/12/12 | Accepted: 2020/04/18 | Published: 2020/04/18

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Clinical Excellence

Designed & Developed by : Yektaweb